I have isolated and characterized two enzymes that are essential for the biosynthesis of all steroid hormones in all steroidogenic tissues:
1. Cholesterol side-chain-cleaving cytochrome P450scc, EC 1.14.15.6
2. Adrenodoxin reductase, EC 1.18.1.6
In addition, I have also characterized P450c11 that catalyzes 11β hydroxylation of steroids in the adrenal cortex:
3. P45011β monooxygenase, EC 1.14.15.4