Israel Hanukoglu, Ph. D.
Rehelim, Israel

Curriculum Vitae

Date and Place of Birth: March 14, 1952, Istanbul, Turkey

Family: Married to Sarah Hanukoglu-Leitman.

Education

1966-1969Ataturk Boys' High School, Istanbul, Turkey.
1969-1970Joseph A. Craig High School, Janesville, Wisconsin, U.S.A.
(Graduation rank: 8th in a class of 459).
1970-1974B.A.Hebrew University of Jerusalem, Israel.
(Cum laude, Majors: Biology and Psychology).
1975-1976M.Sc.University of Wisconsin-Madison, Wisconsin, U.S.A.
(Major: Endocrinology-Biochemistry Emphasis. Thesis: Progesterone metabolism in the pineal, brain stem, thalamus and corpus callosum of the female rat. Major Professors: H. J. Karavolas, and R. W. Goy).
1977-1980Ph.D.University of Wisconsin-Madison, Wisconsin, U.S.A.
(Major: Endocrinology-Biochemistry Emphasis. Thesis: Mechanism of electron transport to cytochrome P-450 in adrenal cortex mitochondrial steroid monooxygenase systems. Major Professors: C. R. Jefcoate and N. L. First).

Positions Held

1975-1980Research Assistant, Departments of Physiological Chemistry, Pharmacology, and Primate Research Center, University of Wisconsin-Madison.
1980-1983Research Fellow/Associate, Department of Biochemistry, The University of Chicago.
1984-1986Lecturer, Department of Biology, Technion-Israel Institute of Technology.
1986-1987Senior Lecturer, Department of Biology, Technion-Israel Institute of Technology.
1987-1993Senior Scientist, Department of Hormone Research, Weizmann Institute of Science.
1993-1995Associate Professor, Department of Hormone Research, Weizmann Institute of Science.
1994-2001Associate Professor, The Research Institute, The College of Judea and Samaria, Ariel.
1995-1997Head of the Social and Life Sciences Program, The College of Judea and Samaria.
1995-1996Associate Professor, Institute of Endocrinology, Sourasky-Tel Aviv Medical Center, Tel-Aviv.
1996-1999Science Adviser to the Prime Minister of Israel.
1999-Founder and Editor, Israel Science and Technology Directory.
2001-2007Professor of Biochemistry and Molecular Biology, The College of Judea and Samaria, Ariel.
2003-2008Founder and Chairman, Department of Molecular Biology, Ariel University Center.
2007-2020Professor of Biochemistry and Molecular Biology, Ariel University.

Academic Family Tree

https://academictree.org/cellbio/tree.php?pid=49656

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Civic and Administrative Functions

1971-1974Elected Representative of the Psychology students (class of about 120 students).
1984Advisor for first year students of Biology in Technion.
1985-1987Representative of the Department of Biology in Computer and Microcomputer Committees in Technion.
1988-1993Elected Representative of the Senior Scientists in the Scientific Council of the Weizmann Institute of Science (elected in five consecutive terms).
1994-1995Editor of "The Academic Zionist", newsletter of Professors for a Strong Israel.
1995-1996Chairman of Professors for a Strong Israel (a non-profit civic organization with about 600 members).
1996-2008Founding member of the Executive Committee of The Ariel Center for Policy Research.
1996-1999Science adviser to the Israeli Prime Minister. In this capacity I represented the Prime Minister's office in the following committees:
  • The Committee of Chief Scientists (of governmental ministries)
  • The National Council for Research and Development
  • Knesset Science and Technology committee
  • The ad hoc Committee of Director Generals (Mankalim) to Advance Science and Technology Education
  • The education sub-committee of the "A computer for every child" project.
2000-2003Chairman, Computing and Information Technology Committee of the College, followed by charimanship of the Internet Committee.
2003-2005Scientific Advisor to the Mayor of Rishon-LeZion for establishing the Boulevard for Jewish Nobel Prize Laureates.
2007Faculty of Natural Sciences, Dean Search Committee Member.
2008Ariel University Center, Vice President Search Committee Member.
2008-2019Member, Ministry of Education Committee for evaluation of Ph.D. theses from abroad.
2016-2020Member, Executive Committee of the Senior Faculty Union.

International Positions

2015-2018Representative of Israel - European Cooperation in Science and Technology (COST) Action Management Committee. ADMIRE COST Action BM1301 Biomedicine and Molecular Biosciences. Aldosterone and mineralocorticoid receptor: Pathophysiology, clinical implication and therapeutic innovations (ADMIRE).

Membership in Editorial Boards

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Reviewer for journals

Verified Reviewer profile at Web of Science

American Journal of Respiratory and Critical Care Medicine
Analytical Biochemistry
Applied Biochemistry and Biotechnology
Archives of Biochemistry and Biophysics
Biochemistry and Molecular Biology Education
Biochimica Biophysica Acta
Bioinformatics
BioMed Research International
BMC Bioinformatics
BMC Biotechnology
BMC Genetics
Cell
Cell & Tissue Research (Springer Nature)
Cells
Cellular Physiology and Biochemistry
Chemical Research in Toxicology
DNA and Cell Biology
Experimental Eye Research
European Journal of Biochemistry
European Respiratory Journal
FEBS Letters
Frontiers in Physiology
Gene
Heliyon
Histology and Histopathology
Hormone Research in Paediatrics
International Archives of Medicine
Journal of Biomedicine and Biotechnology
Journal of Biotechnology
Journal of Cell Communication and Signaling
Journal of Chemical Information and Modeling
Journal of Inorganic Biochemistry
Journal of Molecular Histology
Journal of Pediatric Endocrinology and Metabolism
Journal of Pharmacy and Pharmacology
Journal of Physiology and Pharmacology
Journal of Steroid Biochemistry and Molecular Biology
Journal of Zhejiang University Science (B)
Kidney and Blood Pressure Research
Molecular Biology and Evolution
Molecular and Cellular Endocrinology
Molecular Reproduction and Development
Nucleic Acids Research
Pediatric Nephrology
PLoS ONE
PROTEINS : Structure, Function, and Bioinformatics
Reproduction
Scientific Reports (Nature)

Reviewer for research grant funding agencies

March of Dimes - Birth Defects Foundation
European Science Foundation
German-Israeli Foundation for Scientific Research and Development
Israel Academy of Sciences Basic Research Fund
Israel Cancer Association
Israel Ministry of Science
Israel Science Foundation
Polish Academy of Sciences
TUBITAK - Science and Technology Research Foundation of Turkey
U.S.-Israel Binational Science Foundation

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Functions in International Symposiums

Chairman, The First International Symposium on A Molecular View of Steroid Biosynthesis and Metabolism (supported by a budget of $70,000 by Ares-Serono Symposia), Jerusalem, Israel, October 14-17, 1991.

Vice Chairman, 9th International Symposium on Microsomes and Drug Oxidations, Jerusalem, Israel, July 5-9, 1992.

Program Organizing Committee Member, International Congress of Hormonal Steroids, Dallas, Texas, 1994.

Scientific Committee Member, Eurasian Symposium on Current Trends in Biotechnology: Gene Diagnostics, Gene Therapy, and Informational Immunity, Ankara, Turkey, October 29-November 6, 1995.

Organizing Committee Member, 2nd International Symposium on Molecular Steroidogenesis, Monterey, California, June 7-11, 1996.

Program Organizing Committee Member, The 10th International Congress on Hormonal Steroids, Quebec City, Montreal Canada, June 17-21, 1998.

International Scientific Committee Member, The Third International Symposium on Molecular Steroidogenesis, Nara, Japan August 25-28, 1999.

International Scientific Committee Member, The 4th International Symposium on Molecular Steroidogenesis, Bath, England, April 24-27, 2003.

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Invited Symposiums and Meetings

American Society of Biological Chemists Annual Meeting Minisymposium on Cytochrome P-450, New Orleans, Louisiana, June 5-8, l980.

The American Society for Cell Biology Annual Meeting Minisymposium on Molecular Biology of Cell Function, San Antonio, Texas, November 29-December 3, 1983.

Evolutionary Processes and Theory, International Workshop-Conference, Jerusalem, March 19-28, 1985.

Follicular Development and the Ovulatory Response, Ares-Serono Symposia, Tiberias, April 10-12, 1989.

NATO Advanced Study Institute on Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds, Izmir, Turkey, August 27-September 7, 1989.

National Biochemistry Congress, Antalya, Turkey, November 19-23, 1989.

Tenth International Symposium on Flavins and Flavoproteins, Como, Italy, July 15-20, 1990 (Travel Award).

15th International Congress of Biochemistry, Jerusalem, Israel, August 4-8, 1991.

7th International Conference on Biochemistry and Biophysics of Cytochrome P-450, Moscow, USSR, July 28-August 2, 1991.

9th International Symposium on Microsomes and Drug Oxidations, Jerusalem, Israel, July 5-9, 1992.

National Biochemistry Congress, Antalya, Turkey, October 24-28, 1992.

8th International Conference on Cytochrome P450 Biochemistry Biophysics and Molecular Biology, Lisbon, Portugal, October 24-29, 1993.

Neuroendocrine Immune Mechanisms in Stress. Stockholm, Sweden, October 25-26, 1993.

XVI Meeting of the International Study Group for Steroid Hormones. Wien, Austria, November 28-30, 1993.

2nd Inserm-Weizmann Conference on Molecular Endocrinology. Rehovot, December 5-10, 1993.

Novel Aspects of membrane mediated cellular responses: the roles of reactive oxygens. Tirol, January 8-11, 1994.

Sixth Conference on the Adrenal Cortex. Ardmore, Oklahoma, U.S.A., September 21-24, 1994.

Eurasian Symposium on Current Trends in Biotechnology: Gene Diagnostics, Gene Therapy, and Informational Immunity. Ankara, Turkey, October 29-November 6, 1995.

2nd International Symposium on Molecular Steroidogenesis. Monterey, California, June 7-11, 1996.

Israeli Endocrine Society Meeting. Jerusalem, Israel, 1996.

The Keio University International Symposia for Life Sciences and Medicine. 1996 Conference on Oxygen Homeostasis and its Dynamics. December 8-13, 1996.

NATO Advanced Study Institute on Molecular and applied aspects of oxidative drug metabolizing enzymes. Antalya, Turkey. August 31-September 11, 1997.

International Symposium on Molecular Steroidogenesis. Nara, Japan. August 25-28, 1999.

International Workshop: From Sequence to Function: Experimental and Bioinformatic Studies of Cytochrome P450 Superfamily. Moscow, Russia. July 6-10, 2000.

4th International Workshop on Molecular Steroidogenesis, Bath, England, April 24-27, 2003.

American Physiological Society Conference on "Aldosterone and ENaC: From Genetics to Physiology". Banff, Alberta, Canada. September 10-14, 2003.

6th International Symposium on Aldosterone and the Epithelial Na+ Channel ENaC: From Gene to Disease, Zermatt, Switzerland. October 3-7, 2007. Pediatric Endocrinology Symposium. Tel Aviv, February 2, 2011.

10th Indo-Italian Workshop on Chemistry and Biology of Antioxidants. Sapienza University, Rome, Italy, November 10-12, 2011.

2nd Annual World Congress of Molecular & Cell Biology. Beijing, China, May 18-20, 2012.

51st Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), Leipzig, Germany, September 20-23, 2012.

4th Annual World Congress of Molecular & Cell Biology, Dalian, China, April 25-28, 2014. 8th International

Conference on Structural Genomics - Workshop on Proteopedia. Weizmann Institute of Science, Rehovot, Israel June 7-11, 2015.

Annual Meeting of the European Cooperation in Science and Technology for Aldosterone and mineralocorticoid receptor (COST ADMIRE). Dublin, Ireland March 1-2, 2017.

Past and Present Membership in Professional Societies

1983- American Society for Biochemistry and Molecular Biology
1983- The Endocrine Society (U.S.A.)
1987- Israel Endocrine Society
1989- Israel Biochemical Society
2011- American Physiological Society
1980- University of Wisconsin Alumni Association

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Research Grant Support

1982 U.S.P.H.S. National Cancer Institute Research Service Award. Subject: "Characterization of human epidermal keratin genes". Approximately $20,000 per year for a three year period.

1984 U.S.P.H.S. National Institutes of Health Research Grant Award. Subject: "Molecular genetics of steroid hydroxylase systems". Approximately $200,000.

1988-1993 The Leo and Julia Forscheimer Center for Molecular Genetics grant. Subject: "Isolation and characterization of peptide hormone inducible genes in steroidogenic tissues". $15,000.

1991-1993 Israel Cancer Society grant. Subject: "Identification of Trophic Hormone Regulated Proto-oncogenes". $15,000 per year.

1991-1993 Israel Cancer Research Fund grant. Subject: "Trophic hormone regulation of proto-oncogene expression". $18,000 per year.

1991-1993 Godfrey Foundation Grant for Research on Children's Diseases. Subject: "Molecular genetics of pseudohypoaldosteronism". $26,000 per year.

1992-1993 Kimmelman Center for Biomolecular Structure and Assembly. Subject: Expression of cytochrome P450 system electron transport enzymes for crystallographic analysis".

1992 Joseph Cohn Center for Biomembrane Research. Subject: Characterization of ACTH receptor by molecular cloning". 1992-1994 Israel Academy of Sciences Basic Research Fund grant. Subject "Molecular cloning and characterization of ACTH and MSH receptors". $37,000 per year.

1992-1994 Israel Ministry of Health. Subject: "Pseudohypoaldosteronism: Identification of genetic defects in mineralocorticoid receptor and clinical trial with carbenoxolone." 30,000 N.I.S.

1995-1997 UK-Israel Science and Technology Research Fund. Subject: "Molecular genetic analysis of pseudohypoaldosteronism".

2000-2004 Israel Ministry of Health. Subject: "Characterization of the molecular basis of a salt wasting syndrome (pseudohypoaldosteronism) that results from unresponsiveness to aldosterone".

2008-2011 Israel Ministry of Health. Subject: "Epithelial sodium channels (ENaC): Structure-function relationships and the effect of mutations that cause Pseudohypoaldosteronism on the function of the channels." 100,000 N.I.S. per year.

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Teaching

Courses taught in the past: